Phosphodiesterase-4 Inhibition and Brain Tumor Growth
نویسندگان
چکیده
منابع مشابه
Phosphodiesterase-4 inhibition and brain tumor growth.
To the Editor: We read with great interest the December 1, 2008, article by Goldhoff et al. (1) on the role of cyclic AMP phosphodiesterase-4 (PDE4) in brain tumor growth. The authors found that PDE4 is expressed in human brain tumors of glial and neuronal lineage (glioblastoma, medulloblastoma, ependymoma, and meningioma). In addition, overexpression of PDE4A1, a brain-specific isoform of PDE4...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2009
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-09-0456